Endocrine Abstracts

PKCα has been implicated in different neuronal functions like, apoptosis, synaptic plasticity, and memory formation. PKCα has been linked to control insulin signalling in peripheral tissues as a feedback regulator. However, the exact mechanism how this kinase regulates insulin signalling in neuron is not yet understood completely. Therefore the objective of the present study was to understand the mechanism of action of PKCα on neuronal insulin signalling cascade...